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Chemdea |
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Loxoribine (RWJ 21757) – TLR7 Ligand |
Catalog # CD0198 |
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Price: 10 mg - $45; 25 mg - $75; 50 mg - $195;
100 mg - $325; 250 mg - $750, 1 g - inquire Shipping and handling fee: Within USA - $15; International - $39; Delivery by FedEx |
Availability: In stock |
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7-Allyl-8-oxoguanosine (7,8-Dihydro-8-oxo-7-(2-propenyl)guanosine)
White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS.
Purity: 98% by HPLC. CAS# 121288-39-9. Solubility: DMSO (30
mg/mL), water (10 mg/mL). Molecular Formula: C13H17N5O6. Molecular Weight: 339.3.
Selective ligand
for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes
cytolytic precursor cells for activation by IL-2
Reference: 1. Bekeredjian-Ding, I. B. et al. J. Immunol. 2005,
174, 4043;
2. Lee, J.
et al. PNAS 2003, 100, 6646 ; 3. Pope,
B. L. et al. Cell. Immunol. 1995, 162, 333 ; 4. Goodman, M. G. et al. Blood
1994, 84, 3457 ; 5. Schindler,
U. Mol. Cell. Biol. 1994, 14, 5820 ;
6. Pope, B. L. et al. J. Immunol. 1993,
151, 3007. |
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SAME PRODUCT AS: |
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Cat. No. ALX-480-097 |
Cat. No. N/A |
Cat. No. ALX-480-097 |
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Cat. No. N/A |
Cat. No. 21757 |
Cat. No.
N/A |
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CHEMDEA; |