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Loxoribine (RWJ 21757) TLR7 Ligand

Catalog # CD0198

Price:  10 mg - $45; 25 mg - $75; 50 mg - $195; 100 mg - $325; 250 mg - $750, 1 g - inquire

Shipping and handling fee: Within USA - $15; International - $39; Delivery by FedEx

Availability:  In stock

 

 

7-Allyl-8-oxoguanosine (7,8-Dihydro-8-oxo-7-(2-propenyl)guanosine)

 

White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: 98% by HPLC. CAS# 121288-39-9. Solubility: DMSO (30 mg/mL), water (10 mg/mL). Molecular Formula: C13H17N5O6. Molecular Weight: 339.3.

 

Selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2

 

Reference: 1. Bekeredjian-Ding, I. B. et al. J. Immunol. 2005, 174, 4043; 2. Lee, J. et al. PNAS 2003, 100, 6646 ; 3. Pope, B. L. et al. Cell. Immunol. 1995, 162, 333 ; 4. Goodman, M. G. et al. Blood 1994, 84, 3457 ; 5. Schindler, U. Mol. Cell. Biol. 1994, 14, 5820 ; 6. Pope, B. L. et al. J. Immunol. 1993, 151, 3007.

 

 

SAME PRODUCT AS:

Axxora 

Cat. No. ALX-480-097

 

Cayman Chemical

Cat. No. N/A

 

Enzo Life Sciences 

Cat. No. ALX-480-097

EMD

Cat. No. N/A

Tocris   

Cat. No. 21757

Sigma

Cat. No. N/A

 

 

Caution Not fully tested. For research use only. Not for human use.

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