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VEGFR Tyrosine Kinase Inhibitor II

Catalog # CD0207

Price:  1 mg - $65; 5 mg - $99; 10 mg - $180; 25 mg - $395; 50 mg - $730; 100 mg - $1320

Availability:  In stock

 

 

N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide

 

White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: 99% by HPLC. CAS# 269390-69-4. Solubility: DMSO (5 mg/mL). Molecular Formula: C19H16ClN3O. Molecular Weight: 337.8.

 

 

A potent, cell-permeable, reversible, and ATP-competitive inhibitor of the kinase activities of KDR, Flt-1 and c-Kit (IC50 = 20 nM, 180 nM and 240 nM, respectively), and minimally inhibit c-Src and EGF-R activities (IC50 = 7.0 M and 7.3 M). Also displays antiangiogenic and antitumor properties. Does not inhibit the activities of CDK-1, c-Met, IGF-1R or PKA (IC50 > 10 M).

 

References: Furet, P., et al. Bioorg. Med. Chem. Lett. 2003, 13, 2967.

 

 

SAME PRODUCT AS:

Axxora 

Cat. No. N/A

 

Cayman Chemical  

Cat. No. N/A

Enzo Life Sciences 

Cat. No. N/A

EMD

Cat. No. 676481

Tocris   

Cat. No. N/A

Sigma

Cat. No. N/A

 

 

Caution Not fully tested. For research use only. Not for human use.

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