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4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity:
99% by HPLC. Endotoxin free. CAS# 144875-48-9.
Solubility: DMSO. Molecular Formula: C17H22N4O2. Molecular Weight: 314.4.
R-848 is a
selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and
TLR8 in human. Potent antitumor and antiviral compound. Stimulates antibody
secretion, cytokine production, protection from apoptosis and CD80
upregulation.
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