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Imiquimod TLR7 Ligand

Catalog # CD0115

Price:  50 mg - $35; 100 mg - $49; 250 mg - $95, 1 g - inquire

Shipping and handling fee: Within USA - $15; International - $39; Delivery by FedEx

Availability:  In stock

 

 

1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine

 

White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: 99% by HPLC. CAS# 99011-02-6. Solubility: DMSO (3 mg/mL); warming to 60C is required for complete solubilization. Molecular Formula: C14H16N4. Molecular Weight: 240.3.

 

 

An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo. See also Gardiquimod (Cat# CD0204).

 

Reference: 1. Majewski, S., et al. Int. J. Dermatol. 2005, 44, 14; 2. Gibson, S .J., et al. Cell. Immunol. 2002, 218, 74; 3. Hemmi, H., et al. Nat. Immunol. 2002, 3, 196; 4. Megyeri, K., et al. Mol. Cell. Biol. 1995, 15, 2207.

 

 

SAME PRODUCT AS:

Axxora 

Cat. No. ALX-420-039

 

Cayman Chemical

Cat. No. N/A

 

Enzo Life Sciences 

Cat. No. ALX-420-039

EMD

Cat. No. 401020

Tocris   

Cat. No. 3700

Sigma

Cat. No. N/A

 

 

Caution Not fully tested. For research use only. Not for human use.

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