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Chemdea |
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Imiquimod – TLR7 Ligand |
Catalog # CD0115 |
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Price: 50 mg - $35; 100 mg - $49; 250 mg -
$95, 1 g - inquire Shipping and handling fee: Within USA - $15; International - $39; Delivery by FedEx |
Availability: In stock |
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1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS.
Purity: 99% by HPLC. CAS# 99011-02-6. Solubility: DMSO (3
mg/mL); warming to 60°C is required for complete solubilization. Molecular Formula:
C14H16N4. Molecular Weight: 240.3.
An imidazoquinoline compound that
acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported
to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce
the secretion of several pro-inflammatory cytokines and chemokines
both in vitro and in vivo. See also Gardiquimod (Cat# CD0204).
Reference: 1. Majewski, S., et al. Int. J. Dermatol. 2005, 44, 14; 2. Gibson, S .J., et al. Cell. Immunol. 2002, 218, 74; 3. Hemmi, H., et al. Nat. Immunol. 2002, 3, 196; 4. Megyeri, K., et al. Mol. Cell. Biol. 1995, 15, 2207. |
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SAME PRODUCT AS: |
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Cat. No.
ALX-420-039 |
Cat. No. N/A |
Cat. No. ALX-420-039 |
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Cat. No. 401020 |
Cat. No.
3700 |
Cat. No.
N/A |
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CHEMDEA; |